专利名称:Derivatives from tricyclic amino acids,
process for their preparation, compoundscontaining them and their use, as well asbicyclic amino acids as intermediates andprocess for their preparation
发明人:Urbach, Hansjörg, Dr.,Henning, Rainer,
Dr.,Becker, Reinhard, Dr.
申请号:EP83111079.6申请日:19831107公开号:EP0109020A2公开日:19840523
摘要:the invention relates to a new class of drugs called tricyclic derivatives of theamino acids of the formula 1 in the n = 0 or 1, a = - ch = ch - or - ch2 ch2, r = hydrogen,alkyl or aralkyl, r = hydrogen or alkyl, which may be substituted by amino, acylamino orbenzoylamino can be alkenyl,cycloalkyl, cycloalkenyl, cycloalkyl - alkyl, aryl or arylteilhydriertes, respectively by alkyl, or halogen substituted alkoxy can be aralkyl oraroylalkyl,both as defined above substituted, a mono - orbicyclischer s -, 0 - and \\/ or nheterocyclen residue or a side chain of a possibly protected naturally occurring aminoacid, r2 = hydrogen, alkyl, alkenyl or aralkyl,y = hydrogen or hydroxy, r = hydrogen oroxygen and undz = together undx = alkyl, aryl, alkenyl, cycloalkyl, by alkyl, alkoxy,hydroxy, halogen, nitro, amino, alkylamino,dialkylamino and \\/ or methylendioxy mono -,di - or trisubstituiert can be, or 3 - indolyl mean and their physiologically acceptable salts,processes for their manufacture.the containing means and its use, as well as new
bicyclische amino acids as intermediate, and their production methods.
申请人:HOECHST AKTIENGESELLSCHAFT
地址:65926 Frankfurt am Main DE
国籍:DE
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